Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease.

نویسندگان

  • Yun-Kun Qi
  • Hao-Nan Chang
  • Kai-Mai Pan
  • Chang-Lin Tian
  • Ji-Shen Zheng
چکیده

The first total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease is described by native chemical ligation. Chemical synthesis of azide-labeled proteins would provide useful protein tools for biochemical, biophysical or medical studies.

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عنوان ژورنال:
  • Chemical communications

دوره 51 78  شماره 

صفحات  -

تاریخ انتشار 2015